ANTI-AGING EFFECTS OF METFORMIN | Drugs For Longevity [2020]
Lance Hitchings・10 minutes read
Metformin is a widely used drug for treating type 2 diabetes and is being researched for its potential in improving longevity, with various mechanisms of action including blocking glucose absorption and enhancing insulin sensitivity. Studies suggest it may lower cancer risk by 30-50% and slow tumor growth, but combining it with exercise may not be beneficial.
Insights
- Metformin, a common drug for type 2 diabetes, is not only effective in managing blood sugar levels but also shows promise in reducing cancer risk and potentially slowing tumor growth.
- Despite its potential anti-aging effects, combining metformin with exercise may not be advantageous, as they appear to counteract each other in terms of enhancing fitness, insulin sensitivity, and mitochondrial function.
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Recent questions
What is metformin used for?
Metformin is a commonly prescribed drug for treating type 2 diabetes, especially in overweight individuals. It is considered safe and effective by the World Health Organization.
How does metformin work in the body?
Metformin works by blocking glucose absorption in the intestine, reducing liver glucose production, and improving glucose absorption into muscles. It also enhances insulin sensitivity, decreases fatty acid oxidation suppression by insulin, and activates the AMPK pathway, aiding in fat and sugar burning.
Can metformin lower cancer risk?
Studies suggest that metformin may lower cancer risk by 30-50% and potentially slow tumor growth, making it a promising area of research for cancer prevention and treatment.
Is metformin being studied for anti-aging effects?
Yes, metformin is currently being researched for its potential anti-aging effects, with scientists like David Sinclair and Aubrey de Grey exploring its benefits in improving longevity and overall health.
Is it beneficial to combine exercise with metformin?
Combining exercise with metformin may not be beneficial, as they appear to cancel each other out in terms of improving fitness, insulin sensitivity, and mitochondrial respiration. It is important to consult with a healthcare provider before making any changes to your medication or exercise routine.
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Summary
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Metformin: Diabetes Treatment with Longevity Benefits
- Metformin is a widely used drug for treating type 2 diabetes and is now being researched for its potential in improving longevity.
- It is a first-line medication for diabetes, particularly in overweight individuals, and is considered safe and effective by the World Health Organization.
- Metformin works by blocking glucose absorption in the intestine, reducing liver glucose production, and improving glucose absorption into muscles.
- It also enhances insulin sensitivity, decreases fatty acid oxidation suppression by insulin, and activates the AMPK pathway, which aids in fat and sugar burning.
- Studies suggest metformin may lower cancer risk by 30-50% and potentially slow tumor growth.
- Metformin is being studied for its anti-aging effects, with researchers like David Sinclair and Aubrey de Grey taking it for its potential benefits.
- However, combining exercise with metformin may not be beneficial, as they seem to cancel each other out in terms of improving fitness, insulin sensitivity, and mitochondrial respiration.
