Digestion and Absorption in One Shot - NEET/Class 11th Boards

PW English Medium2 minutes read

Human physiology covers various body systems, with the first chapter focusing on nutrition, the process of ingesting food for energy production through digestion and absorption. The text delves into the details of how ingestion, digestion, absorption, assimilation, and egestion work in human nutrition, highlighting the importance of enzymes, glands, organs like the stomach, liver, pancreas, and small intestine, and common issues like malnutrition, jaundice, and indigestion.

Insights

  • Human physiology focuses on digestion, absorption, and nutrition, where ingested food is broken down into simpler forms for energy production.
  • Teeth play a crucial role in digestion, with different types like incisors, canines, premolars, and molars serving distinct functions in chewing and grinding food.
  • The pancreas is a vital organ in digestion, producing enzymes like lipase, amylase, and nucleases for breaking down lipids, starches, and nucleic acids.
  • Absorption in the gut involves various mechanisms like simple diffusion, facilitated transport, and active transport for different nutrients, with the small intestine being the primary site for absorption.

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Recent questions

  • What is the process of human nutrition?

    Human nutrition involves ingestion, digestion, absorption, assimilation, and egestion.

  • What are the main components of human teeth?

    Human teeth consist of enamel, dentine, pulp cavity, and different types like incisors, canines, premolars, and molars.

  • How does the stomach aid in digestion?

    The stomach churns and digests food, storing it for 3-4 hours, producing acidic chyme.

  • What are the functions of the pancreas in digestion?

    The pancreas produces alkaline enzyme juice for digestion and hormones like insulin and glucagon.

  • What are the main functions of the small intestine in nutrient absorption?

    The small intestine absorbs nutrients through simple diffusion, facilitated transport, and active transport, mainly in the duodenum, jejunum, and ileum.

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Summary

00:00

Human Physiology: Nutrition, Digestion, Absorption, Assimilation, Egestion

  • Human physiology encompasses various systems in the body, including digestion and absorption.
  • The first chapter of human physiology delves into nutrition, which involves ingesting food for energy production.
  • Humans are heterotrophs, relying on heterotrophic nutrition, where organisms do not produce their own food.
  • Holozoic nutrition involves ingesting food through the mouth, not diffusion, and breaking down large molecules into smaller ones for digestion.
  • Nutrition initiates with ingestion, where food particles are taken into the mouth and chewed.
  • Digestion follows ingestion, breaking down large molecules into simpler, absorbable forms through mechanical and chemical processes.
  • Absorption occurs next, with digested food entering the blood for distribution to body tissues.
  • Assimilation involves the food becoming part of body cells after absorption, providing energy or storage.
  • Egestion is the final step, removing undigested food particles as feces from the intestine.
  • Nutrients in food are categorized into macronutrients (carbohydrates, proteins, fats) for energy and micronutrients (vitamins, minerals, water) for metabolism and protection.

18:31

"Oral cavity anatomy and digestion process"

  • Digestion is a biochemical and mechanical process.
  • The oral cavity is separated from the nasal cavity by the bony palate.
  • The bony palate leads to the softer palate, which ends in the uvula.
  • The uvula covers the nasal cavity while eating to prevent food from entering.
  • The oral cavity contains teeth and the tongue, which has taste buds on papillae.
  • The tongue helps in speech, mixing food, cleaning teeth, and tasting.
  • The pharynx is a common chamber for food and air, with nasopharynx, oropharynx, and laryngopharynx sections.
  • The epiglottis covers the glottis while eating to prevent food from entering the trachea.
  • Human dentition includes bunodont, thecodont, diphyodont, and heterodont types.
  • Teeth are embedded in sockets in the alveolar bone, with enamel as the hardest substance and dentine as the second hardest, containing a pulp cavity with blood vessels and nerves.

35:48

Types and Development of Human Dentition

  • Dentine is secreted by odontoblast cells and is embedded in the socket in codon type of dentition.
  • Heterodont dentition consists of different types of teeth like incisors, canines, premolars, and molars.
  • Incisors have one root, canines have one root, premolars have two roots in the upper jaw and one root in the lower jaw, and molars have three roots in the upper jaw and two roots in the lower jaw.
  • Milk teeth appear first in children, followed by permanent teeth after the milk teeth fall off.
  • Milk teeth are also known as primary or deciduous teeth, while permanent teeth are called secondary or adult teeth.
  • Dental formula indicates the number and types of teeth in each half of the upper and lower jaws.
  • Mono-firidon dentition means teeth appear only once in life, while di-firidon dentition means teeth appear twice in life.
  • The dental formula for mono-firidon teeth is 2-1-2-3/2-1-2-3, while for di-firidon teeth, it is 3-1-2-3/3-1-2-3.
  • The epiglottis is a cartilaginous flap that prevents food from entering the glottis.
  • The esophagus has upper and lower esophageal sphincters, with the lower one also known as the cardiac or gastroesophageal sphincter.

52:09

Stomach anatomy and digestive functions explained

  • The stomach is divided into fundus, body, cardia, and pylorus.
  • The sphincter between the stomach and small intestine is called the pyloric sphincter.
  • The stomach churns and digests food, storing it for 3-4 hours.
  • Acidic food in the stomach is called chyme.
  • The esophagus lacks glands, while the stomach has gastric glands.
  • Gastric glands contain chief/peptic, auxintic/parietal, mucous, and argentafin cells.
  • Chief cells produce enzymes, including zymogens like pepsinogen and prorenin.
  • Auxintic cells produce HCl and intrinsic factor, maintaining stomach pH at 1.8.
  • Mucous cells protect the stomach lining from acid erosion.
  • Argentafin cells, like G cells, produce gastrin hormone, stimulating gastric secretion and motility.

01:10:53

Anatomy of Small Intestine and Colon

  • Serosa is composed of visceral peritoneum and mesothelium, which is epithelium with connective tissue.
  • Muscularis layer consists of outer longitudinal and inner circular muscles.
  • Submucosa does not have rugae, formed by mucosa, and Brunner's gland is present in the submucosa.
  • The small intestine is divided into duodenum, jejunum, and ileum, with the duodenum being C-shaped.
  • The cecum is a blind tube-like structure with an ileocecal valve preventing backflow into the ileum.
  • The vermiform appendix is a vestigial structure containing symbiotic microorganisms producing vitamins B and K.
  • The colon includes ascending, transverse, descending, and sigmoid parts, leading to the rectum and anus.
  • The anus is surrounded by internal and external sphincters, with the internal being involuntary and the external voluntary.
  • Intestinal glands in the small intestine are present in the crypts of Lieberkühn, containing Paneth, mucus-secreting, and endocrine cells.
  • Intestinal juice, known as succus entericus, contains enzymes for digesting carbohydrates, proteins, nucleotides, and lipids.

01:28:13

Digestive System Anatomy and Functions

  • Working remarkably and differently from others requires increased hard work towards a goal, setting one apart as a winner.
  • Enzymes play a crucial role in the body's functions.
  • Villi in the intestines have extensions of lamina propria, containing blood vessels like arterioles, venules, and a central lacteal lymph vessel for fat absorption.
  • Intestinal villi contain artery, veins, and lacteal.
  • Mucosal epithelium has goblet cells secreting mucus for lubrication, villi increase surface area, gastric glands secrete prorenin and pepsinogen, and intestinal glands are present in crypts.
  • Salivary glands produce saliva, with three pairs - parotid, submandibular, and sublingual - each with specific duct names like Stensen's duct for parotid gland.
  • Saliva composition includes water, enzymes like salivary amylase and lysozyme, antibodies, urea, and ions.
  • Sublingual gland is below the tongue, parotid near the cheek, submandibular near the large jaw, and submaxillary near the cheek.
  • Liver produces bile for fat emulsification, detoxifies, produces blood proteins, stores iron, and converts glucose into glycogen and performs gluconeogenesis.
  • Pancreas, with exocrine and endocrine functions, produces alkaline enzyme juice for digestion and hormones, with the main pancreatic duct opening into the duodenum through the hepatopancreatic duct.

01:46:08

Pancreas: Enzymes, Insulin, Glucose Metabolism, Digestion

  • The pancreas secretes alkaline pancreatic juice containing enzymes like nucleases (DNase and RNase) for digesting nucleic acids.
  • It also produces lipase (pancreatic lipase) and pancreatic amylase (also known as amylopsin).
  • Inactive enzymes like trypsinogen, chymotrypsinogen, and procarboxypeptidase are present in the pancreas.
  • The pancreas is a compound organ with both exocrine and endocrine functions, secreting insulin and glucagon for glucose metabolism.
  • Insulin decreases blood glucose levels, while glucagon increases blood glucose levels.
  • Somatostatin is another hormone produced by the endocrine portion of the pancreas.
  • Parietal cells secrete hydrochloric acid and intrinsic factor, aiding in erythropoiesis.
  • The small intestine contains enzymes like sucrase and lactase for digesting sucrose and lactose into glucose and fructose.
  • Protein digestion starts in the stomach with pepsin breaking down proteins into proteoses and peptones.
  • In the small intestine, enzymes like trypsin, chymotrypsin, and carboxypeptidase convert proteoses and peptones into dipeptides and then amino acids.

02:03:41

Digestive Enzymes and Absorption in Gut

  • Intestinal lipase converts lipids into glycerol and fatty acids, fully digesting lipids.
  • Pancreatic DNases digest DNA, which is consumed when eating plants like onions.
  • DNase breaks down DNA into nucleotides, then nucleotidase converts them into nucleosides by removing phosphate.
  • Nucleosides are further converted into nitrogenous bases and sugars, forming nucleotides.
  • Pancreatic amylase digests 70% of starch into maltose, while salivary amylase digests 30%.
  • Lactase breaks down lactose into glucose and galactose.
  • Insulin, somatostatin, and glucagon are endocrine components of the pancreas.
  • Absorption in the gut involves simple diffusion for glucose and amino acids, facilitated transport for fructose, and active transport for glucose and amino acids using ATP.
  • Lipids are absorbed as glycerol and fatty acids, forming triglycerides in enterocytes, then conjugating with phosphate and proteins to form chylomicrons.
  • Absorption occurs mainly in the small intestine, with the large intestine absorbing water, drugs, and minerals.

02:21:11

Digestive System Disorders and Functions

  • Vomiting is a reflex action controlled by the medulla, triggered by stomach cell stimulation, leading to stomach content ejection.
  • Jaundice results from bilirubin accumulation in the blood due to bile duct blockage, causing yellow skin and eyes.
  • Constipation arises from irregular bowel movements, leading to hard feces formation and difficulty in defecation.
  • Diarrhea involves frequent bowel movements, resulting in increased water loss and reduced food absorption.
  • Indigestion occurs when food is improperly digested, often due to contaminated food or stress, hindering enzyme secretion.
  • Malnutrition includes marasmus affecting infants under one year, leading to impaired growth and thinning limbs due to protein and calorie deficiency.
  • Kwashiorkor affects older children, causing muscle wasting, edema, and prominent ribs due to protein deficiency.
  • Inflammation in the intestinal tract is common due to bacterial, viral, or parasitic infections like hookworms.
  • The small intestine is the primary organ for nutrient absorption, with fats forming micelles for absorption in the enterocyte mucosal epithelium.
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