This Is Your Body On Cannabis
Institute of Human Anatomy・15 minutes read
The endocannabinoid system integrates various anatomical systems, influencing the body's response to cannabinoids like THC and CBD through receptors, endogenous cannabinoids, and enzymes. THC primarily affects CB1 receptors in the brain, influencing functions like decision-making, while CBD shows potential medicinal properties like reducing inflammation but is overshadowed by overselling in CBD products.
Insights
- The endocannabinoid system acts as a crucial subsystem in the human body, integrating various anatomical systems and influencing responses to cannabinoids like THC and CBD, with receptors like CB1 and CB2 playing key roles.
- The rise in mainstream interest in the endocannabinoid system due to cannabis legalization has led to increased research opportunities, especially in treating psychiatric disorders like PTSD, but concerns exist regarding the overselling of CBD products lacking proper regulation and quality control, despite their potential medicinal benefits.
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Recent questions
What is the endocannabinoid system?
A subsystem integrating anatomical systems, influenced by cannabinoids.
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Summary
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Endocannabinoid System: Integrating Body's Response to Cannabinoids
- The human body comprises various anatomical systems, such as the nervous system, digestive system, and cardiovascular system, each with distinct roles.
- The endocannabinoid system acts as a subsystem integrating these anatomical systems, influencing the body's response to cannabinoids like THC and CBD.
- The endocannabinoid system consists of cannabinoid receptors, endogenous cannabinoids, and enzymes involved in their creation and breakdown.
- Cannabinoid receptors, like CB1 and CB2, are found in different densities throughout the body, with CB1 receptors most concentrated in the brain.
- CB1 receptors are abundant in regions like the cerebral cortex, hypothalamus, and cerebellum, affecting functions like motor control and memory.
- CB2 receptors are primarily located in peripheral tissues, including lymphatic and immune tissues, regulating inflammation through immune cells like B cells and T cells.
- Endocannabinoids, like 2-AG and anandamide, are produced by the body and modulate neurotransmitter release and inflammation in various systems.
- Phytocannabinoids, such as THC and CBD, bind to cannabinoid receptors, with THC primarily affecting CB1 receptors in the brain, influencing areas like decision-making and empathy.
- CBD, a non-psychoactive cannabinoid, interacts with different receptors than THC, showing potential medicinal properties like reducing inflammation.
- The characteristic high from consuming cannabinoids is complex, influenced by the interaction of various endocannabinoids and exocannabinoids with receptors throughout the body, leading to different types of highs.
14:23
CBD's potential for psychiatric disorders under scrutiny.
- The endocannabinoid system is gaining mainstream attention, with cannabis legalization allowing for more scientific and medical research, particularly in treating psychiatric disorders like PTSD. However, there is concern about overselling CBD products, despite their potential, due to the prevalence of items labeled as CBD without proper regulation or quality control.
