The “heroic dose” of psychedelics, according to Johns Hopkins | Dr. Matthew Johnson

Recent questions

• What are psychedelics and how do they differ from traditional antidepressants?

  Psychedelics are a unique drug class known for their profound impacts on individuals' lives, contrasting with traditional antidepressants that may not always provide the same benefits. While antidepressants work by altering brain chemistry over time, psychedelics like psilocybin can induce intense, short-term experiences that may lead to lasting changes in perception, mood, and behavior.

• How has society's perception of psychedelics evolved over time?

  The 1960s marked the emergence of psychedelics, sparking societal changes and fears. However, modern society is more open to exploring these compounds, recognizing their rich history across various cultures and disciplines. While early controversies and unethical research led to a halt in psychedelic studies, current research focuses on their medical applications, particularly in therapy.

• What is the history of psychedelics and their influence on different fields?

  Psychedelics have a rich history across various cultures and disciplines, influencing fields like biology, arts, and music. Early research by groups like the "Spring Grove Group" and researchers like Abram Hoffer and Humphrey Osmond laid the foundation for psychedelic therapy, highlighting the diverse impact these compounds have had on human understanding and creativity.

• What is the current focus of research on psychedelics?

  Current research on psychedelics, particularly psilocybin, focuses on their medical applications for therapeutic purposes. Studies have shown that doses ranging from 30 to 40 milligrams can lead to profound insights and potential therapeutic benefits when administered in a carefully prepared environment that encourages trust, letting go, and openness during the psychedelic experience.

• What is the therapeutic process involving psychedelics?

  The therapeutic process involving psychedelics like psilocybin includes careful preparation, creating a warm environment, and encouraging patients to trust, let go, and be open during the psychedelic experience. This approach aims to facilitate profound insights and potential therapeutic benefits by allowing individuals to explore their thoughts, emotions, and perceptions in a safe and supportive setting.