Rhonda Patrick on the CRAZY Longevity Benefits of Vitamin D

FoundMyFitness Clips2 minutes read

Vitamin D deficiency affects human gene regulation, with 70% of the population having levels below 30 nanograms per milliliter easily remedied by affordable supplements. Low vitamin D levels are linked to accelerated aging, higher mortality risks, and can be improved with daily 4,000 IU supplements, with the optimal range being 40 to 60 nanograms per milliliter.

Insights

  • Vitamin D deficiency affects over 5% of the human genome, impacting gene regulation, and is prevalent in about 70% of the population due to various factors like sunscreen use, limited UVB exposure, aging, and indoor lifestyles.
  • Low levels of vitamin D are linked to increased mortality risks, with studies showcasing a direct correlation between deficiency and higher mortality rates. Additionally, supplementing with 4,000 IU of vitamin D daily can reduce epigenetic age in individuals with deficiency and overweight issues.

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Recent questions

  • How prevalent is vitamin D deficiency?

    Vitamin D deficiency is widespread, affecting about 70% of the population with inadequate levels below 30 nanograms per milliliter.

  • What are the factors contributing to vitamin D deficiency?

    Factors include UVB radiation blockage, living in northern latitudes, aging, and indoor lifestyles.

  • How does vitamin D deficiency affect aging?

    Vitamin D deficiency accelerates aging, as evidenced by studies in mice and its importance in human health.

  • What are the risks associated with low vitamin D levels?

    Low vitamin D levels are linked to higher mortality risks, as shown by observational data and genetic variation studies.

  • How can vitamin D deficiency be addressed?

    Vitamin D deficiency can be remedied by affordable supplements, with the ideal range being 40 to 60 nanograms per milliliter.

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Summary

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"Vitamin D Deficiency: Impact, Solutions, and Health"

  • Vitamin D deficiency is widespread and crucial due to its role in regulating genes, affecting over 5% of the human genome, leading to improper gene activation or repression.
  • About 70% of the population has inadequate levels of vitamin D, which is below 30 nanograms per milliliter, easily remedied by affordable supplements.
  • Factors contributing to deficiency include UVB radiation blockage by sunscreen or melanin, living in northern latitudes with limited UVB exposure, aging reducing skin's efficiency in producing vitamin D, and modern indoor lifestyles.
  • Studies show that vitamin D deficiency accelerates aging in mice, emphasizing its importance in human health.
  • Observational data links low vitamin D levels to higher mortality risks, but randomized studies using genetic variations show a direct correlation between low vitamin D levels and increased mortality rates.
  • A study on African-American individuals with vitamin D deficiency and overweight issues showed that a daily 4,000 IU vitamin D supplement reduced their epigenetic age by almost 2 years, with the ideal vitamin D level range being 40 to 60 nanograms per milliliter.
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