Pharmacokinetics: How Drugs Move Through the Body
Professor Dave Explains・5 minutes read
Pharmacokinetics involves drug movement in the body through absorption, distribution, metabolism, and excretion, impacting bioavailability and dosage determination through various processes like inactivation in the liver.
Insights
- Pharmacokinetics encompasses drug movement in the body, including absorption, distribution, metabolism, and excretion, crucial for understanding drug effects and interactions.
- Metabolism, a key aspect of pharmacokinetics, involves liver-mediated chemical reactions that can inactivate drugs, affecting bioavailability and dosage, highlighting the liver's pivotal role in drug processing.
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Recent questions
What does pharmacokinetics involve?
The movement of drugs in the body.
How do drugs enter the body?
Through membranes, bloodstream, or digestive system.
What is distribution in pharmacokinetics?
Movement of drugs through the bloodstream.
Where does drug metabolism occur?
Often in the liver through hepatic portal system.
What impacts drug bioavailability?
Absorption, distribution, and metabolism.
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Summary
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Drug movement in body: absorption, distribution, metabolism
- Pharmacokinetics involves the movement of drugs within the body, encompassing absorption, distribution, metabolism, and excretion.
- Absorption details how drugs enter the body, whether through membranes, the bloodstream, or the digestive system, with bioavailability indicating the proportion absorbed.
- Distribution explains how drugs move through the bloodstream, influenced by interactions with blood components and anatomical barriers like the blood-brain barrier.
- Metabolism involves chemical reactions that inactivate drugs, often occurring in the liver through the hepatic portal system, impacting drug bioavailability and dosage determination.
