Dr. Svante Pääbo「An Ancient DNA View of Human Origins」
JapanPrize・2 minutes read
Modern humans originated in Africa, spreading out around 70 thousand years ago and interacting with Neanderthals and Denisovans, leading to genetic contributions impacting modern humans. Research on Neanderthal DNA reveals variants affecting health outcomes, including a progesterone receptor variant linked to pregnancy complications and a risk factor for severe illness from viruses, with global implications during the pandemic.
Insights
- Genetic studies have revealed that modern humans carry about 2% Neanderthal DNA, showing interactions and interbreeding between the two groups as they spread globally.
- Neanderthal genetic variants impact modern humans, with a progesterone receptor variant linked to both premature births and protection against miscarriages, highlighting the complex effects of ancient DNA on present-day health outcomes.
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Recent questions
How did modern humans originate?
In Africa 2-4 hundred thousand years ago, spreading globally.
What is the relationship between Neanderthals and modern humans?
Neanderthals are the closest evolutionary relatives to present-day humans.
What is the significance of Neanderthal DNA in modern humans?
Neanderthal DNA impacts modern humans, influencing traits and health.
How do Neanderthal variants affect health outcomes?
Neanderthal variants can influence health outcomes, such as preterm birth.
What insights do genetic studies provide about Neanderthals and Denisovans?
Genetic studies reveal origins, interactions, and impacts of Neanderthals and Denisovans.
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