Come pensa un’intelligenza artificiale? | Giulio Deangeli | TEDxBari

TEDx Talks2 minutes read

Giulio De Angeli from the University of Cambridge utilizes AI in biomedical research to identify pathology mechanisms, reflecting a broader trend where AI significantly enhances productivity in various fields, including healthcare. With advancements like GPT and generative AI, the integration of these technologies is transforming the medical landscape by managing vast data and improving decision-making processes, despite the high financial risks associated with drug development.

Insights

  • Giulio De Angeli emphasizes the transformative potential of AI in biomedical research, particularly its ability to analyze vast amounts of medical data and streamline processes, which can significantly enhance drug development efficiency despite the high costs and low approval rates traditionally associated with the pharmaceutical industry.
  • The evolution of AI technologies, such as the introduction of the Transformer architecture and generative AI, not only improves the accuracy and creativity of tasks like text generation but also opens new avenues in healthcare, allowing for innovative patient triage solutions and increasing productivity across various professions, while still underscoring the irreplaceable role of human judgment in complex scenarios.

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Recent questions

  • What is artificial intelligence in simple terms?

    Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, particularly computer systems. These processes include learning, reasoning, and self-correction. AI can be categorized into two main types: narrow AI, which is designed for specific tasks, and general AI, which aims to perform any intellectual task that a human can do. In practical applications, AI is used in various fields, including healthcare, finance, and transportation, to enhance efficiency and decision-making. The technology relies on algorithms and large datasets to learn from patterns and make predictions or decisions without human intervention.

  • How does deep learning work?

    Deep learning is a subset of machine learning that utilizes neural networks with many layers to analyze various forms of data. It mimics the way the human brain operates, processing information through interconnected nodes or neurons. In deep learning, data is fed into the network, where it undergoes transformations through multiple layers, each extracting different features or patterns. The network adjusts its internal parameters based on the errors in its predictions, improving its accuracy over time. This technique is particularly effective for tasks such as image and speech recognition, where traditional algorithms may struggle to achieve high performance.

  • What are the risks of drug development?

    The risks of drug development are significant, primarily due to the high costs and low success rates associated with bringing a new drug to market. On average, developing a new drug can cost around $1 billion, with some oncology drugs exceeding $4 billion. This financial burden is compounded by the fact that only about 10% of drugs that enter human trials receive approval from regulatory agencies. The approval rates are even lower for drugs targeting neurodegenerative diseases, with a mere 0.4% success rate from 2003 to 2012. These statistics highlight the challenges pharmaceutical companies face in balancing innovation with financial viability.

  • What is generative AI used for?

    Generative AI is a type of artificial intelligence that focuses on creating new content by learning from existing data. It employs architectures like autoencoders and generative adversarial networks (GANs) to produce outputs such as images, music, or text that resemble the training data. This technology has gained popularity for its ability to generate realistic and diverse content, making it useful in various applications, including art, design, and entertainment. Generative AI can also assist in fields like drug discovery by simulating molecular structures or predicting biological interactions, thereby accelerating research and development processes.

  • How is AI changing healthcare?

    AI is transforming healthcare by enhancing the efficiency and accuracy of medical practices. It can manage vast amounts of medical data, create standardized clinical datasets, and assist healthcare professionals by automating routine tasks, allowing them to focus on more complex patient issues. For instance, AI tools can analyze patient data to provide insights for diagnosis and treatment, improving patient outcomes. Additionally, innovations like AI-driven triage systems enable patients to choose between consulting a doctor or a bot, reflecting the growing integration of AI in clinical settings. As technology continues to evolve, significant advancements in AI are expected to further revolutionize healthcare delivery.

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Summary

00:00

AI Innovations in Biomedical Research and Drug Development

  • Giulio De Angeli, a researcher at the University of Cambridge, applies AI methods to biomedical research, focusing on identifying pathology mechanisms since arriving in 2016.
  • Traditional AI, or discriminative AI, primarily involves deep learning techniques, specifically neural networks, which perform classification and regression tasks on datasets.
  • Classification involves training a neural network to categorize data, such as identifying animals, while regression estimates numerical values, like predicting an animal's height.
  • Neural networks simulate neuron functions by taking input signals, multiplying them by weights, summing them, and applying a threshold to determine output signals.
  • The cost to market a new drug averages around $1 billion, with some oncology drugs exceeding $4 billion, highlighting the financial risks in pharmaceutical development.
  • Statistically, the probability of a drug being approved after human trials is only about 10%, with neurodegenerative disease drugs having a mere 0.4% approval rate from 2003 to 2012.
  • Generative AI, discussed in the media, uses architectures like autoencoders to create new content by training on existing data, such as generating new images from learned patterns.
  • The Transformer architecture, introduced in 2017, utilizes attention mechanisms to filter important information, significantly improving tasks like text generation, leading to models like GPT.
  • GPT models, trained on vast datasets from the internet, utilize powerful computing resources, with current models operating on 30,000 GPUs, showcasing unprecedented scalability.
  • The probabilistic nature of GPT's text generation, which selects from multiple likely outcomes rather than the most probable, results in more varied and human-like text outputs.

14:35

AI Revolutionizing Healthcare and Professional Productivity

  • The introduction of non-determinism in AI models, particularly through temperature adjustments, enhances their ability to analyze texts semantically, which is crucial for medical applications.
  • AI can help manage vast medical data, create standardized clinical datasets, and assist doctors by saving time on routine cases, allowing focus on complex patient issues.
  • In 2017, London allowed patients to choose between a doctor or a bot for triage, highlighting the rapid evolution of AI in healthcare, with significant advancements expected soon.
  • AI tools can increase productivity significantly; for instance, programmers using AI can triple their output, creating a competitive necessity for adaptation in the workforce.
  • The future of professions like programming may simplify, as natural language processing allows easier access to coding, but human decision-making will remain essential in creative and clinical contexts.
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