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Can a keto diet eliminate cancer growth? Dr. Thomas Seyfried says yes

Target Cancer・35 minutes read

Dr. Thomas Seyfried discusses targeting cancer cells by starving them of fermentable fuels like glucose and glutamine, transitioning the body to a ketotic state to protect normal cells while targeting cancer cells. The goal is to prolong the lives of cancer patients with a high quality of life by utilizing a press pulse therapeutic strategy that combines diet and drugs in a specific sequence for optimal synergy without toxicity.

Insights

  • Cancer cells rely on glucose and glutamine for fermentation metabolism, making them vulnerable to starvation by removing these fermentable fuels.
  • The press pulse therapeutic strategy, involving consistent glucose reduction and intermittent glutamine targeting, can effectively target tumor cells while sparing the immune system, showcasing a promising approach to cancer treatment with reduced toxicity levels.

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Recent questions

  • How do cancer cells obtain energy?

    Cancer cells rely on glucose and glutamine for fermentation metabolism, not on oxygen like normal cells. This unique metabolic process allows cancer cells to thrive and grow rapidly by utilizing fermentable fuels.

  • What is the press pulse therapeutic strategy?

    The press pulse therapeutic strategy involves consistently reducing glucose levels while pulsing glutamine targeting drugs to starve cancer cells of their fermentable fuels. This approach aims to target tumor cells effectively while protecting normal cells and the immune system, ultimately prolonging the lives of stage four cancer patients.

  • Why is ketosis beneficial in targeting cancer cells?

    Transitioning the body to a ketotic state protects normal cells while targeting cancer cells by preventing them from using fatty acids and ketones as fuel. This metabolic state inhibits cancer cells' ability to grow and proliferate, making them more vulnerable to treatments that starve them of fermentable fuels.

  • How does chronic inflammation contribute to cancer development?

    Chronic inflammation from factors like obesity and processed foods can damage mitochondria, leading to oxidative phosphorylation dysfunction and cancer development. Maintaining a healthy lifestyle and diet is crucial in preventing mitochondrial injury and reducing the risk of cancer.

  • What lifestyle changes can help prevent cancer?

    Following a metabolic approach to cancer management, such as maintaining a low-carb, high-exercise lifestyle in ketosis, can reduce the likelihood of cancer development. Avoiding highly processed carbohydrates, engaging in physical activity, and reducing chronic inflammation through healthy choices can contribute to overall health and vitality while lowering the risk of cancer.

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Summary

00:00

Starving Cancer Cells: Targeting Fermentable Fuels

  • Dr. Thomas Seyfried discusses targeting cancer cells by starving them of fermentable fuels.
  • Cancer cells rely on glucose and glutamine for fermentation metabolism.
  • Tumor cells do not use oxygen for energy but rely on fermentation.
  • Cyanide does not kill tumor cells as they do not use oxygen.
  • Cancer cells can be starved by removing their fermentable fuels.
  • Transitioning the body to a ketotic state protects normal cells while targeting cancer cells.
  • Ketosis prevents cancer cells from using fatty acids and ketones as fuel.
  • Cancer cells have deficient oxidative phosphorylation, making them dependent on fermentation.
  • Anti-angiogenic drugs do not work as cancer cells do not need increased blood flow.
  • The press pulse strategy involves reducing glucose consistently and pulsing glutamine targeting drugs.

13:29

"Ketosis and Glutamine Inhibition Target Cancer"

  • Tumor cells are initially slaughtered, but the immune system is not killed by glutamine deprivation, only stunned and paralyzed.
  • Removing the glutamine drug allows the immune system to reactivate and clear dead tumor cells, requiring a time period for the process.
  • Reintroducing glutamine or not removing the drug may rescue some tumor cells, but their growth is significantly slowed due to glucose inhibition.
  • The immune system, once recovered from a small dose of glutamine inhibitor, can be targeted again to degrade tumor cells dependent on fermentation metabolism.
  • Utilizing low doses of cytotoxic chemotherapy in nutritional ketosis can effectively target tumor cells with reduced toxicity levels.
  • The press pulse therapeutic strategy involves combining diet and drugs like glutamine and glucose inhibitors in a specific sequence for optimal synergy without toxicity.
  • The goal is to prolong the lives of stage four cancer patients with a high quality of life, focusing on maintaining health and vitality through ketosis and exercise.
  • Historical records of aboriginal tribes and chimpanzees suggest that a low-carb, high-exercise lifestyle in ketosis reduces the likelihood of cancer due to healthy mitochondria.
  • Chronic inflammation from factors like obesity and processed foods can damage mitochondria, leading to oxidative phosphorylation dysfunction and cancer development.
  • Mitochondrial injury from chronic inflammation and carcinogens is the root cause of cancer, emphasizing the importance of maintaining a healthy lifestyle to prevent cancer development.

26:59

"Metabolic Approach: Diet Impacts Chronic Diseases"

  • Following a metabolic approach to cancer management leads to improvements in cardiovascular disease, type two diabetes, and hypertension alongside cancer.
  • The Mediterranean Diet has been linked to reducing cancer, dementia, and cardiovascular disease due to the absence of highly processed carbohydrate foods.
  • Highly processed carbohydrates are the key factor in neutralizing the therapeutic benefits of a Mediterranean diet.
  • Fast food options like Subway sandwiches, Dunkin' Donuts, and others counteract the health benefits of a Mediterranean diet due to their highly processed nature.
  • The prevalence of fast food chains and processed foods contributes to societal health issues like obesity, diabetes, and cancer.
  • The combination of poor diet, lack of exercise, and stress impacts mitochondrial health, leading to various chronic diseases.
  • Physical activity, even in short bursts throughout the day, is crucial for maintaining cardiovascular health and preventing diseases like heart attacks and strokes.
  • Maintaining sustained ketosis through diet choices, such as carnivore, Mediterranean, or vegetarian diets, can be achieved by avoiding highly processed carbohydrates.
  • Ketone ester solutions can temporarily induce ketosis, but sustained ketosis with low glucose levels is more therapeutic for overall health.
  • The modern lifestyle and diet choices diverge significantly from the evolutionary adaptations that favored survival, leading to chronic health issues in society.

39:50

"Glucose Ketone Index: Key to Health"

  • The GKI, or Glucose Ketone Index, is a tool used with a carnivore diet and specific low-glycemic vegetables to monitor health status, particularly for cancer patients and individuals aiming to maintain optimal mitochondrial health. To calculate the GKI, divide blood glucose by 18 and then by the millimolar of ketones, with the Keto Mojo device simplifying this process by providing a direct reading.
  • Dr. Seyfried emphasizes the importance of the GKI for overall health, especially in preventing chronic diseases, and directs individuals to find more information on their research in peer-reviewed journals like Cureus and PubMed.
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