David Sinclair’s 2024 REVISED Supplement Protocol | Critical Changes!!

Wellness Messiah with Rimon20 minutes read

Dr. David Sinclair adjusted his supplement routine, now focusing on fisetin, NMN, resveratrol, and spermidine, alongside new additions like fish oil and taurine. He also incorporates Metformin and rapamycin into his regimen for health and longevity benefits.

Insights

  • Dr. David Sinclair has adjusted his supplement routine, focusing on fisetin, NMN, resveratrol, alpha-lipoic acid, spermidine, and fish oil, among others, to target senescent cells and optimize longevity.
  • Sinclair's experiment with taurine and addition of trimethyl glycine (TMG) showcase his commitment to studying the impact of these compounds on aging and health, highlighting his continuous exploration of novel approaches to enhance well-being.

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Recent questions

  • What changes did Dr. David Sinclair make to his supplement routine?

    Dr. David Sinclair made two major changes to his supplement routine from 2020 to 2022. He used to take both fisetin and quercetin to target senescent cells but recently dropped one of them. Sinclair now only mentions taking fisetin, with a dosage of 500 milligrams to 1,000 milligrams per day.

  • What supplements has Dr. David Sinclair consistently taken for years?

    Dr. David Sinclair has been consistently taking resveratrol and alpha-lipoic acid for years. He takes 1 gram of NMN daily, aligning with his circadian rhythms for optimal effect. Sinclair also continues to take 1 gram of resveratrol daily, mixed with coconut yogurt in the morning.

  • What new supplement did Dr. David Sinclair add to his routine?

    Dr. David Sinclair added spermidine to his routine, taking 1 to 2 milligrams daily. Fish oil, specifically omega-3, is a recent addition to Sinclair's routine, with a dosage of 2 grams of EPA and 1.5 grams of DHA daily.

  • What is the purpose of Dr. David Sinclair's experiment with taurine?

    Taurine is a new experiment for Dr. David Sinclair, with a daily intake of 2 grams, aiming to study its impact on longevity and health benefits. Chronic taurine prevents full activation of mtor, potentially impacting aging stages; Dr. David Sinclair experimented with 2 grams of taurine daily.

  • What is the significance of trimethyl glycine (TMG) in Dr. David Sinclair's routine?

    Dr. David Sinclair added trimethyl glycine (TMG) to counteract potential nicotinamide issues from NAD boosters. TMG provides methyl groups for body functions and protection against stress. Dr. Sinclair takes Metformin for diabetes prevention and longevity benefits, consuming 1 gram daily; he also uses rapamycin to target mtor, possibly aiding protein recovery post-exercise.

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Summary

00:00

Dr. Sinclair's Updated Supplement Routine 2022

  • Dr. David Sinclair has made two major changes to his supplement routine in 2020 to 2022.
  • He used to take both fisetin and quercetin, targeting senescent cells, but recently dropped one of them.
  • Sinclair now only mentions taking fisetin, with a dosage of 500 milligrams to 1,000 milligrams per day.
  • Resveratrol and alpha-lipoic acid are supplements Sinclair has been consistently taking for years.
  • Sinclair takes 1 gram of NMN daily, aligning with his circadian rhythms for optimal effect.
  • He also continues to take 1 gram of resveratrol daily, mixed with coconut yogurt in the morning.
  • Sinclair has added spermidine to his routine, taking 1 to 2 milligrams daily.
  • Fish oil, specifically omega-3, is a recent addition to Sinclair's routine, with a dosage of 2 grams of EPA and 1.5 grams of DHA daily.
  • Sinclair still takes vitamin D and K2, but the specific dosages are not mentioned.
  • Taurine is a new experiment for Sinclair, with a daily intake of 2 grams, aiming to study its impact on longevity and health benefits.

14:36

Dr. Sinclair's Anti-Aging Drug and Supplement Regimen

  • Chronic torine prevents full activation of mtor, potentially impacting aging stages; Dr. David Sinclair experimented with 2 grams of ill torine daily.
  • Dr. Sinclair added trimethyl glycine (TMG) to counteract potential nicotinamide issues from NAD boosters; TMG provides methyl groups for body functions and protection against stress.
  • Dr. Sinclair takes Metformin for diabetes prevention and longevity benefits, consuming 1 gram daily; he also uses rapamycin to target mtor, possibly aiding protein recovery post-exercise.
  • Dr. Sinclair's drug regimen includes Metformin, baby aspirin for health, and rapamycin for aging; dosages vary, with Metformin at 1,000 mg most days.
  • Dr. Sinclair's supplement routine includes NN, El torine, spermidine, resveratrol, fisetin, vitamin D, vitamin K2, alpha-lipoic acid, and fish oil; magnesium is recommended for overall health and longevity.
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