Sperm Death in the Uterus

Nucleus Medical Media2 minutes read

During ovulation, sperm swim through the cervix towards the uterus, facing destruction by the woman's immune system, with only a few thousand making it to the fallopian tube where chemicals make them hyperactive to reach the egg, resulting in only a few dozen out of the original 300 million sperm successfully fertilizing the egg.

Insights

  • The female reproductive system poses significant challenges for sperm, as many are destroyed by the immune system, and only a fraction successfully reach the egg due to various obstacles and hurdles.
  • Chemical signals in the reproductive tract play a crucial role in enhancing sperm motility and guiding them towards the egg, ensuring that only a small number out of the millions released during ejaculation have the opportunity to fertilize the egg.

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Recent questions

  • How do sperm reach the egg?

    Through thinned cervical mucus and muscular contractions.

  • What is the role of the woman's immune system in fertilization?

    Destroys many sperm during the journey.

  • How do chemicals in the reproductive tract affect sperm?

    Make sperm hyperactive to reach the egg.

  • What happens to sperm in the fallopian tube?

    Only a few thousand reach the fallopian tube.

  • How many sperm typically reach the egg?

    Only a few dozen out of 300 million.

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Summary

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Sperm's Journey to Fertilization

  • Sperm pass through the cervix during ovulation, swimming through thinned cervical mucus towards the uterus, where muscular contractions aid their journey. However, many sperm are destroyed by the woman's immune system, with only a few thousand reaching the fallopian tube. Chemicals in the reproductive tract make the sperm hyperactive, helping them reach the egg, with only a few dozen out of the original 300 million sperm successfully reaching the egg.
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