Rheumatoid arthritis - causes, symptoms, diagnosis, treatment, pathology
Osmosis from Elsevier・2 minutes read
Osmosis offers personalized study plans for medical learning, while rheumatoid arthritis is an inflammatory disorder affecting joints and other organ systems. Genetic and environmental factors trigger autoimmune processes in rheumatoid arthritis, leading to joint inflammation and damage, as well as various extra-articular manifestations.
Insights
- Osmosis offers personalized study plans for medicine learners, integrating videos, practice questions, and flashcards to enhance understanding and retention.
- Rheumatoid arthritis, an inflammatory condition affecting joints and organs, is influenced by genetic factors like HLA-DR1 and HLA-DR4, leading to autoimmune processes involving protein citrullination, immune cell activation, and joint inflammation with potential extra-articular complications.
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Recent questions
What is Osmosis?
Osmosis is a platform that simplifies medical learning through personalized study plans, videos, practice questions, and flashcards.
What is rheumatoid arthritis?
Rheumatoid arthritis is an inflammatory disorder that affects joints and other organ systems, characterized by joint inflammation, pannus formation, and cartilage damage.
What is the function of articular cartilage?
Articular cartilage in healthy joints acts as a protective cushion, helping to reduce friction and absorb shock during movement.
How do synovial joints like the knee connect bones?
Synovial joints like the knee connect bones through a fibrous joint capsule and synovial membrane, which help provide stability and allow for smooth movement.
What triggers rheumatoid arthritis?
Rheumatoid arthritis is triggered by a combination of genetic factors like HLA-DR1 and HLA-DR4 interacting with environmental factors, leading to autoimmune processes, citrullination of proteins, and immune cell confusion.
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Summary
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Understanding Rheumatoid Arthritis: Causes and Symptoms
- Osmosis simplifies the learning of medicine by creating personalized study plans with videos, practice questions, and flashcards.
- Rheumatoid arthritis is an inflammatory disorder affecting joints and other organ systems.
- Healthy joints have articular cartilage acting as a protective cushion.
- Synovial joints like the knee connect bones with a fibrous joint capsule and synovial membrane.
- Rheumatoid arthritis is triggered by genetic factors like HLA-DR1 and HLA-DR4 interacting with environmental factors.
- Autoimmune processes in rheumatoid arthritis involve citrullination of proteins, leading to immune cell confusion and antibody production.
- In rheumatoid arthritis, T-helper cells and antibodies cause joint inflammation, leading to pannus formation and cartilage damage.
- Extra-articular manifestations of rheumatoid arthritis include fever, rheumatoid nodules, atherosclerosis, anemia, and lung complications.
