How to make your organs last longer | Quin Wills | TEDxNoVA
TEDx Talks・13 minutes read
A machine named Betty can keep human livers alive outside the body for up to five days, while researchers in Manhattan are modifying these machines to extend the lifespan of livers for transplantation. By injecting livers with RNA medicine, scientists aim to reprogram donor organs and develop transformative therapies using AI algorithms, potentially revolutionizing the treatment of chronic liver diseases.
Insights
- Betty is a cutting-edge machine that can preserve human livers outside the body for up to five days, offering a potential solution to the pressing need for organ transplants.
- Researchers in Manhattan are leveraging RNA medicine and AI algorithms to revolutionize liver preservation and treatment, paving the way for more effective therapies for chronic liver diseases and aging-related health challenges.
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Recent questions
How long can Betty keep a human liver alive?
Up to five days
What is the focus of research on liver disease?
Developing transformative medicines
How are therapies for chronic diseases traditionally tested?
Animal models and clinical trials
What is the goal of combining human expertise with AI algorithms in liver research?
Accelerate therapy development
Why are chronic diseases of aging becoming more prevalent?
Longer lifespans
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Summary
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"Revolutionizing Liver Health with Cutting-Edge Technology"
- Betty is a machine that can keep a human liver alive outside the body for up to five days, using cutting-edge technology.
- A team of scientists, technologists, and clinicians in Manhattan are modifying liver machines to keep livers alive for extended periods.
- Livers are injected with RNA medicine, programmed to change gene behavior and target specific liver cells, reprogramming donor organs for transplantation.
- Liver disease can progress silently until liver failure necessitates a transplant, with statistics indicating a high prevalence of liver issues.
- Chronic diseases of aging, like liver disease, are becoming more prevalent due to longer lifespans, posing significant health challenges.
- Research focuses on developing transformative medicines to extend health span and address aging-related diseases effectively.
- Traditional methods of hypothesis generation and testing for therapies involve animal models and clinical trials, which are costly and time-consuming.
- Innovative approaches involve studying livers at scale, using AI algorithms to understand liver function, and creating human liver models for testing therapies.
- By combining human expertise with AI algorithms, researchers aim to accelerate the development of effective therapies for chronic diseases, potentially transforming millions of lives.
